SMCC

General description

Heterobifunctional reagent useful for enzyme labeling of antibodies and antibody fragments. Cross-links both a sulfhydryl group and a free amine group. Useful for sequential conjugation to minimize polymerization.

Heterobifunctional reagent useful for enzyme labeling of antibodies and antibody fragments. Reacts with primary amines and sulfhydryl groups.

Warning

Toxicity: Irritant (B)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Caruelle, D., et al. 1988. Anal. Biochem.173, 328.
Nashat, A.H., et al. 1998. Biotechnol. Bioeng.60, 137.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Molecular Weight: 334.32. Empirical Formula: C₁₆H₁₈N₂O₆. Assay: ≥. 97% (HPLC). Quality Level: 100. form: solid. manufacturer/tradename: Calbiochem^®. . storage condition: OK to freeze, desiccated. color: white. solubility: DMF: 10 . mg/mL, acetonitrile: soluble. shipped in: ambient. storage temp.: −. 20°C. InChI: 1S/C16H18N2O6/c19-12-5-6-13(20)17(12)9-10-1-3-11(4-2-10)16(23)24-18-14(21)7-8-15(18)22/h5-6,10-11H,1-4,7-9H2. InChI key: JJAHTWIKCUJRDK-UHFFFAOYSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.