SLF TFA (C007B-419042)

Catalog No.: C007B-419042
Manufacturer No.: S655339-1ml
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

SLF TFA is a synthetic ligand for FK506-binding protein (FKBP) with an affinity of 3.1 μM for FKBP51 and an IC 50 of 2.6 μM for FKBP12. SLF TFA can be used in the synthesis of PROTAC .In VitroThree scout fragments-KB02, KB03, and KB05 are fused, which cover two different electrophile groups (chloroacetamide and acrylamide) and display broad cysteine reactivity in the human proteome-to the SLF ligand that binds tightly and selectively to FKBP12, a cytosolic prolyl isomerase that has been frequently used to study ligand-induced protein degradation. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Specifications and Purity: 10mM in DMSO

Molecular Formula: C32H41F3N2O8

Molecular Weight: 638.67

UPC:: 42311510
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: S655339-1ml
CAS:: 2378802-47-0
Product Size:: 1ml

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