SK1-IN-1 is a potent sphingosine kinase 1 ( SPHK1 ) inhibitor with an IC 50 of 58 nM.In VivoSK1-IN-1 demonstrates significant improvement in the intrinsic clearance, particularly against human liver microsomes. SK1-IN-1 is selected for rat PK studies and demonstrates modest in oral bioavailability with acceptable half-lives in blood circulation . MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:IC50: 58 nM (SPHK1).
Specifications and Purity: ≥98%
Molecular Formula: C22H30N4O3
Molecular Weight: 398.50
PubChem CID: 46911228
Isomeric SMILES: C[C@@H](C1=CC=C(C=C1)C2=NOC(=N2)CCC3CCCC3)NC(=O)[C@@H]4[C@H](CCN4)O
- UPC:
- 41104415
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- S647764-25mg
- CAS:
- 1218816-71-7
- Product Size:
- 25mg
akash.verma@cenmed.com
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