Silvestrol aglycone is a Silvestrol analogue, inhibits protein translation initiation in cancer cells, with EC 50 s of 10 and 200 nM for myc-LUC and tub-LUC luciferase reporter protein translation, respectively. Anti-cancer activity.In VitroSilvestrol aglycone (Compound 4) inhibits the proliferation of MDA-MB-231 cells with an E 50 of 20 ± 10 nM after 72 h. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid.
Specifications and Purity: ≥99%
Molecular Formula: C27H26O8
Molecular Weight: 478.49
PubChem CID: 24178739
Isomeric SMILES: COC1=CC=C(C=C1)[C@]23[C@@H]([C@H]([C@H]([C@]2(C4=C(O3)C=C(C=C4OC)O)O)O)C(=O)OC)C5=CC=CC=C5
- UPC:
- 10161813
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- S648945-5mg
- CAS:
- 960365-65-5
- Product Size:
- 5mg
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