InformationSildenafil Mesylate is a mesylate form of Sildenafil, an inhibitor ofPhosphodiesterase 5.TargetsPDE5In vivoChronic sildenafil treatment increases the detumescence phase in young and aged rats (p<0.05), although aged rats show a greater increase than young rats. Baseline cavernous PDE5 expression and activity are greater in aged vs young rats (p<0.05). After chronic sildenafil treatment cavernous PDE5 expression is increased in young (p<0.05) but not in aged rats. Chronic and acute sildenafil treatment similarly inhibits PDE5 activity in the penis of young and aged rats (p<0.05), coincident with its free plasma concentrations equivalent to clinically therapeutic ranges.
Specifications and Purity: ≥98%
Molecular Formula: C22H30N6O4S.xCH4O3S
Molecular Weight: 474.58(free base)
PubChem CID: 135425271
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/S413169-SCI_7f23cc8bfdfbbb861e8f9093014d0d9b.pdf
- UPC:
- 51182007
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- S413169-1g
- CAS:
- 1308285-21-3
- Product Size:
- 1g
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