DescriptionSIAB is an amine- and sulfhydryl-reactive heterobifunctional crosslinker and Sulfo-SIAB is its water-soluble analog. These crosslinkers contain an amine-reactive N-hydroxysuccimide (NHS) ester and a sulfhydryl-reactive iodoacetyl group, and are often used for preparing enzyme conjugates or immunotoxins. Water-soluble and water-insoluble forms of NHS esters have essentially identical reactivity. Sulfo-SIAB is supplied as a sodium salt and is water-soluble to ~10mM. SIAB must be first dissolved in an organic solvent, such as DMSO or DMF, and then added to the aqueous reaction mixture. SIAB is lipophilic, membrane-permeable and does not possess a charged group.
Specifications and Purity: ≥97%
MDL Number: MFCD00054976
Molecular Formula: C13H11IN2O5
Molecular Weight: 402.14
PubChem CID: 126367
Isomeric SMILES: C1CC(=O)N(C1=O)OC(=O)C2=CC=C(C=C2)NC(=O)CI
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/S487253-SCI_f96651a7b9c498b3f42241239f6feedf.pdf
- UPC:
- 51111602
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- S487253-50mg
- CAS:
- 72252-96-1
- Product Size:
- 50mg
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