SGK1-IN-1 (C007B-418007)

Catalog No.: C007B-418007
Manufacturer No.: S647642-5mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

SGK1-IN-1 is a highly active and selective inhibitor of SGK-1 , with an IC 50 of 1 nM.In VitroSGK1-IN-1 (14n) shows an acceptable SGK isoform selectivity with a good activity on hSGK2 and a moderate activity on the hSGK3, with IC 50 s of 1, 41 nM at 10 μM and 50 μM ATP concentration, respectively. SGK1-IN-1 also displays cellular activity in a SGK1-dependent phosphorylation of GSK3β assay in U2OS cells with activities of 0.69 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:SGK1.

Specifications and Purity: ≥99%

Molecular Formula: C17H12ClFN6O2S

Molecular Weight: 418.83

PubChem CID: 71506845

Isomeric SMILES: C1=CC(=CC=C1C2=NC3=NNC(=C3N=C2)N)NS(=O)(=O)C4=C(C=CC(=C4)Cl)F

UPC:: 42172002
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: S647642-5mg
CAS:: 1279829-87-6
Product Size:: 5mg

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