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sgc2085

SGC2085 (C007B-273110)

Catalog No.
C007B-273110
Manufacturer No.
S422238-1ml
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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InformationSGC2085 SGC2085 is a potent and selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) inhibitor with an IC50 value of 50 nM and >:100-fold selective over other PRMTs.TargetsCARM1 (Cell-free assay) 50 nMIn vitroWith the

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InformationSGC2085 SGC2085 is a potent and selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) inhibitor with an IC50 value of 50 nM and >100-fold selective over other PRMTs.TargetsCARM1 (Cell-free assay) 50 nMIn vitroWith the exception of PRMT6 (IC50 = 5.2 μM), SGC2085 does not inhibit other PRMTs. Although CARM1(PRMT4) is previously shown to asymmetrically dimethylate BAF155 at R1064, no cellular activity is observed for SGC2085 when tested up to 10 μM. The absence of cellular activity for SGC2085 may due to poor permeability.Cell Research(from reference)Cell lines：HEK293 cells Concentrations：up to 10 μM Incubation Time：48 h.

Specifications and Purity: 10mM in DMSO

Molecular Formula: C19H24N2O2

Molecular Weight: 312.41

PubChem CID: 121231417

Isomeric SMILES: CC1=CC(=CC(=C1)OC2=C(C=C(C=C2)CNC(=O)[C@H](C)N)C)C

UPC:
42202001
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
S422238-1ml
CAS:
1821908-48-8
Product Size:
1ml

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