Selumetinib (AZD6244) is a potent, highly selective MEK1 inhibitor with IC50 of 14 nM, also inhibits ERK1/2 phosphorylation with IC50 of 10 nM, no inhibition to p38α, MKK6, EGFR, ErbB2, ERK2, B-Raf, etc. Phase 3.A MEK-1 non-ATP competitive inhibitor.
Specifications and Purity: ≥99%
Molecular Formula: C17H15BrClFN4O3
Molecular Weight: 457.69
PubChem CID: 10127622
Isomeric SMILES: CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/S125580-SCI_6f7923e4ca6f75e56e504100eeaf10b6.pdf
- UPC:
- 41102702
- Condition:
- New
- HazmatClass:
- Yes
- WeightUOM:
- LB
- MPN:
- S125580-100mg
- CAS:
- 606143-52-6
- Health Hazards:
- Corrosive
- Product Size:
- 100mg
- Hazard Statement Codes:
- H411:H373:H361:H318:H317
- Precautionary Statement Codes:
- P501:P405:P362+P364:P333+P313:P305+P351+P338:P302+P352:P391:P280:P273:P272:P261:P260
akash.verma@cenmed.com
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