Biochem/physiol Actions
Selexipag is a potent, highly selective and orally available nonprostanoid agonist for the PGI2 receptor (IP receptor). Selexipag is readily hydrolyzed to the active metabolite ACT-333679 (MRE-269), which is also a potent and selective agonist at IP receptors. In contrast to the prostacyclin analogs iloprost and beraprost, selexipag and metabolite ACT-333679 does not contract gastric fundus up to mM concentrations.
- UPC:
- 42182308
- Condition:
- New
- HazmatClass:
- No
- MPN:
- SML3605-50MG
- CAS:
- 475086-01-2
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