SELENIUM DIOXIDE (SUBLIMED) FOR SYNTHESI (C005B-002049)

Application

Selenium dioxide (SeO₂) is mainly used to oxidize the activated carbon-bearing positions (α-methylene carbon atoms), particularly at allylic or propargylic sites. The more substituted end of the double bond undergoes oxidation.
It can also be used as an oxidizing reagent to synthesize:

• Amides by oxidative amidation of aldehydes with amines.
• Tropone from cycloheptatriene in the presence of potassium dihydrogen phosphate.
• Acetyltetrahydrobenzofurans by oxidation of conjugated dienones.
• 9-hydroxy-undec-10-ynoate from methyl undec-10-ynoate.

Analysis Note

Assay (iodometric): ≥ 98.0 %

Molecular Weight: 110.96. Empirical Formula: O₂Se. vapor pressure: <. 1 Pa ( 20 °C). Quality Level: 200. form: crystals. potency: 68.1 . mg/kg LD₅₀, oral (Rat). reaction suitability: reagent type: oxidant. pH: 2 (20 . °C, 10 . g/L in H₂O). mp: 340 . °C. solubility: 1353 . g/L. density: 3.95 . g/cm³ . at 20 . °C. storage temp.: 2-30°C. InChI: 1S/O2Se/c1-3-2. InChI key: JPJALAQPGMAKDF-UHFFFAOYSA-N. Pictograms: GHS06,GHS08,GHS09. Signal Word: Danger. Hazard Statements: H301 + H331 - H373 - H410. Precautionary Statements: P260 - P264 - P273 - P301 + P310 - P304 + P340 + P311 - P314. Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2. Storage Class Code: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable.