A selective and reversible inhibitor of IKK2 (IC50 = 3- 12 &muM) that displays >10-fold selectivity over 28 other kinases attenuates NF-&kappaB-mediated gene expression in synovial fibroblasts, smooth muscle cells, and astrocytes.
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A selective and reversible inhibitor of IKK2 (IC50 = 3- 12 μM) that displays >10-fold selectivity over 28 other kinases; attenuates NF-κB-mediated gene expression in synovial fibroblasts, smooth muscle cells, and astrocytes.
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