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sc-236 (c15-1848-681)

SC-236 (C005B-432790)

Catalog No.
C005B-432790
Manufacturer No.
PZ0106-25MG
Manufacturer Name
Sigma-Aldrich
Quantity
25
Unit of Measure
MG

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Application SC-236 has been used as a COX-2 inhibitor to study its effects on the mechano-reflex in rats. Biochem/physiol Actions SC-236 exhibits anti-tumor activity in gastric cancer cells by modulating activator protein-1 (AP-1) expression

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Application

SC-236 has been used as a COX-2 inhibitor to study its effects on the mechano-reflex in rats.

Biochem/physiol Actions

SC-236 exhibits anti-tumor activity in gastric cancer cells by modulating activator protein-1 (AP-1) expression and by blocking the anchorage-independent cell growth. It also exhibits a protective effect against cartilage damage by minimizing the inflammation and pain in osteoarthritis. It is also reported to treat allergic inflammation.

SC-236 is a cyclooxygenase-2 (COX-2) inhibitor.

Other Notes

This compound was developed by Pfizer for Lipid Signaling research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold for research purposes under agreement from Pfizer Inc.

Pfizer is a registered trademark of Pfizer, Inc.

UPC:
41116104
Condition:
New
HazmatClass:
Yes
MPN:
PZ0106-25MG
CAS:
170569-86-5

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