SB 242084 is a selective, competitive and high-affinity (pKi=9.0) 5-HT2C receptor antagonist (crosses the blood-brain barrier). SB 242084 increases basal activity of dopaminergic neurons in the ventral tegmental area (VTA) of the midbrain and dopamine release in the vomeronasal nucleus. SB 242084 also increases mitochondrial gene expression and oxidative metabolism via 5-HT2A receptor. SB 242084 has good research potential in the negative symptoms of anxiety, depression and schizophrenia, as well as in acute organ damage.
Specifications and Purity: ≥98%
Molecular Formula: C21H19ClN4O2
Molecular Weight: 394.85
PubChem CID: 16219981
Isomeric SMILES: CC1=CC2=C(C=C1Cl)N(CC2)C(=O)NC3=CN=C(C=C3)OC4=C(N=CC=C4)C.Cl.Cl
- UPC:
- 10161556
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- S168053-10mg
- CAS:
- 181632-25-7
- Product Size:
- 10mg
akash.verma@cenmed.com
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