SB 204741 (C005B-377797)

Catalog No.: C005B-377797
Manufacturer No.: S0693-10MG
Manufacturer Name: Sigma-Aldrich
Quantity: 10
Unit of Measure: MG

Application SB 204741 has been used as a 5-hydroxytryptamine receptor 2B (Htr2B) antagonist: to inhibit Htr2b signaling to test its effect on hepatic stellate cell (HSC) activation in three-month-old adult zebrafish to test its effect on the

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Description
Specifications

Application

SB 204741 has been used as a 5-hydroxytryptamine receptor 2B (Htr2B) antagonist:

to inhibit Htr2b signaling to test its effect on hepatic stellate cell (HSC) activation in three-month-old adult zebrafish
to test its effect on the inhibition of fluoxetine effects in depressive-like behavioral studies in mice
to test its effect in reducing scratching behavior evoked by sertraline in mice

Biochem/physiol Actions

SB 204741 reduces the synaptic facilitation induced by the low dose of buprenorphine in spinal C-fiber synapses.

5-HT_2B serotonin receptor antagonist.

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold for research purposes under agreement from GlaxoSmithKline

UPC:: 85111616
Condition:: New
HazmatClass:: No
MPN:: S0693-10MG
CAS:: 152239-46-8

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