SB 202190 (C007B-263462)

SB 202190 is a pyridinyl imidazole that inhibits the p38 pathway. The compound inhibits the isoforms p38α and p38β. SB 202190 has displayed the ability to activate CPP32-like caspases and induce apoptosis. Research demonstrates that when one residue of ERK2, a related p38 not inhibited by pyridinyl imidazoles, is changed it allows SB 202190 to bind. Studies have revealed that SB 202190 can improve leukemia cell growth by activating MEK/MAPK, as well as phosphorylate and activate MLK3.An inhibitor of the isoforms p38α and p38β.

Specifications and Purity: ≥99%

MDL Number: MFCD00941964

Molecular Formula: C20H14FN3O

Molecular Weight: 331.34

PubChem CID: 5169

Isomeric SMILES: C1=CC(=CC=C1C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)O

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