SANT-1 directly binds to Smoothened (Smo) receptor with Kd of 1.2 nM and inhibits Smo agonist effects with IC50 of 20 nM.Treatment of Anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma cells2 and chronic lymphocytic leukemia cells3 with SANT-1 induced cell death.
Specifications and Purity: ≥98%
Molecular Formula: C23H27N5
Molecular Weight: 373.49
PubChem CID: 6878030
Isomeric SMILES: CC1=C(C(=NN1C2=CC=CC=C2)C)/C=N/N3CCN(CC3)CC4=CC=CC=C4
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/S129830-SCI_022ba1fb62f6054f22f9ce5430a5fd46.pdf
- UPC:
- 10161545
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- S129830-25mg
- CAS:
- 304909-07-7
- Product Size:
- 25mg
akash.verma@cenmed.com
(732) 447-1115





