Name: SALVINORIN A
SKU: C005B-082233
Availability: OutOfStock

SALVINORIN A

Catalog No.

C005B-082233

Manufacturer No.

5081590001

Manufacturer Name

Calbiochem

Quantity

Unit of Measure

A highly potent and selective non-alkaloid positive allosteric modulator of Κ-opioid receptors (K i = 4.3 nM and 16 nM for native and cloned κ-opioid receptors, respectively).

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Description
Specifications

General description

A highly potent and selective non-alkaloid positive allosteric modulator of Κ-opioid receptors (K_i = 4.3 nM and 16 nM for native and cloned κ-opioid receptors, respectively). Also acts as a D2DR partial agonist (K_i = 5-10 nM). Used in studies of addition.

Biochem/physiol Actions

Primary Target
k opioid receptor

Warning

Toxicity: Standard Handling (A)

Other Notes

Roth, B. et al., 2002. PNAS.99, 11934.
Valdés III., j., et al., 1984. J. Organic Chem.49, 4716.
Ortega, A., et al., 1982. J. of Chem. Society, Perkins Transactions I. 2505.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Molecular Weight: 432.46. Empirical Formula: C₂₃H₂₈O₈. Assay: ≥. 98% (HPLC). Quality Level: 100. form: solid. potency: 4.3 . nM K_i. manufacturer/tradename: Calbiochem^®.. storage condition: OK to freeze, protect from light. color: white. solubility: ethanol: 10 . mM, DMSO: 50 . mM. storage temp.: −. 70Â°C. InChI: 1S/C23H28O8/c1-12(24)30-16-9-15(20(26)28-4)22(2)7-5-14-21(27)31-17(13-6-8-29-11-13)10-23(14,3)19(22)18(16)25/h6,8,11,14-17,19H,5,7,9-10H2,1-4H3/t14-,15-,16-,17-,19-,22-,23-/m0/s1. InChI key: OBSYBRPAKCASQB-AGQYDFLVSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3.