(S)-(+)-2-HYDROXY-3-METHYLBUTYRIC ACID 99% (99% EE/GLC) (C005B-022104)

Application

A useful chiral building block for peptide synthesis. Used in the preparation of the cytotoxic didemnin cyclopeptides and of the antineoplastic agent dolastatin 15.

Molecular Weight: 118.13. Empirical Formula: C₅H₁₀O₃. linearFormula: (CH₃)₂CHCH(OH)CO₂H. Quality Level: 200. Assay: 99%. form: solid. optical activity: [α. ]20/D +19°, c :  . 1 in chloroform. optical purity: ee: 99% (GLC). bp: 124-125 . °C/13 . mmHg (lit.). mp: 68-70 . °C (lit.). SMILES string: CC(C)[C@H](O)C(O): O. InChI: 1S/C5H10O3/c1-3(2)4(6)5(7)8/h3-4,6H,1-2H3,(H,7,8)/t4-/m0/s1. InChI key: NGEWQZIDQIYUNV-BYPYZUCNSA-N. Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H315 - H319 - H335. Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338. Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves.