Biochem/physiol Actions
RTC13 is a cell-permeable thiazolidinone derivative that promotes ribosomal read-through activity of premature termination codons (PTCs) and effectively restores full-length protein production from transcripts containing nonsense mutations-generated PTCs, including ataxia-telangiectasia (A-T) mutated in A-T lymphoblastoid cell cultures and dystrophin in mdx Duchenne muscular dystrophy (DMD) mice-derived muscle myotubes.
- UPC:
- 41106313
- Condition:
- New
- HazmatClass:
- No
- MPN:
- SML1725-25MG
- CAS:
- 1359825-94-7
akash.verma@cenmed.com
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