InformationRoxadustat (FG-4592) Roxadustat (FG-4592) is an HIF-α prolyl hydroxylase inhibitor in a cell-free assay, stabilizes HIF-2 and induces EPO production. Roxadustat potentiates RSL3 induced ferroptosis . Phase 3.In vitroFG-4592 is an oral inhibitor of hypoxia inducible factor (HIF) prolyl hydroxylase currently in clinical development for the treatment of anemia. FG-4592 stabilizes the activities of HIF, a cytosolic transcription factor, leading to activation of the genes associated with erythropoiesis, including erythropoietin and enzymes involved in iron metabolism.In vivoCell Datacell lines:MCF-7 cellsConcentrations:Incubation Time:Powder Purity:≥99%.
Specifications and Purity: 10mM in DMSO
Molecular Formula: C19H16N2O5
Molecular Weight: 352.34
- UPC:
- 41116013
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- R408843-1ml
- CAS:
- 808118-40-3
- Product Size:
- 1ml
akash.verma@cenmed.com
(732) 447-1115





