RO27-3225 TFA is potent and selective melanocortin 4 receptor (MC4R) agonist with an EC 50 of 1 nM and 8 nM for MC4R and MC1R , respectively. RO27-3225 TFA shows ~30-fold selectivity for MC4R over MC3R . RO27-3225 TFA has neuroprotective and anti-inflammaIC50& Target:MC4RIn Vivo:RO27-3225 (0.012-0.048mg/kg; intravenous injection; Wistar rats) treatment reverses haemorrhagic shock, reduces multiple organ damage and improves survival. RO27-3225 could have a protective role against multiple organ failure following circulatory shockBiological Activity:RO27-3225 TFA is potent and selective melanocortin 4 receptor (MC4R) agonist with an EC 50 of 1 nM and 8 nM for MC4R and MC1R , respectively. RO27-3225 TFA shows ~30-fold selectivity for MC4R over MC3R . RO27-3225 TFA has neuroprotective and anti-inflamma.
Specifications and Purity: 10mM in DMSO
Molecular Formula: C41H53F3N12O8
Molecular Weight: 898.93
- UPC:
- 41113402
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- R661578-1ml
- Product Size:
- 1ml
akash.verma@cenmed.com
(732) 447-1115





