RMC-0331 (C007B-415797)

Catalog No.: C007B-415797
Manufacturer No.: R648791-50mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

RMC-0331 (RM-023) is a potent, selective and orally bioavailable SOS1 inhibitor. RMC-0331 is an in vivo tool compound that blocks RAS activation via disruption of the RAS-SOS1 interaction.In VitroRMC-0331 has an IC 50 of 71 nM measuring by the rate of GDP/GTP exchange in vitro. MCE has not independently confirmed the accuracy of these methods. They are for reference only.In VivoRMC-0331 (100-250 mg/kg; p.o.; qd; immunocompetent mice) shows single agent anti-tumor activity in SHP2-mutant models . MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:Solid.

Specifications and Purity: ≥98%

Molecular Formula: C22H25ClF3N5O3

Molecular Weight: 499.91

PubChem CID: 155687064

UPC:: 12141730
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: R648791-50mg
CAS:: 2488788-52-7
Product Size:: 50mg

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