RIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC 50 s of 16 nM and 10 nM for RIP1 and ADP-Glo kinaseIC50&:
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RIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC 50 s of 16 nM and 10 nM for RIP1 and ADP-Glo kinaseIC50& Target:IC50: 16 nM (RIP1) and 10 nM (ADP-Glo).
Specifications and Purity: 10mM in DMSO
Molecular Formula: C23H23N5O2
Molecular Weight: 401.46
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