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RIBAVIRIN (C005B-381461)

Catalog No.
C005B-381461
Manufacturer No.
R9644-50MG
Manufacturer Name
Sigma-Aldrich
Quantity
50
Unit of Measure
MG

General description Analog of the imidazole nucleotide intermediates in purine nucleotide biosynthesis. Chemical structure: nucleoside Biochem/physiol Actions Antiviral agent used against a wide variety of human viral infections, in particular,

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General description

Analog of the imidazole nucleotide intermediates in purine nucleotide biosynthesis.

Chemical structure: nucleoside

Biochem/physiol Actions

Antiviral agent used against a wide variety of human viral infections, in particular, chronic hepatitis C, HIV, and adenovirus. Its metabolite, ribavirin 5′-phosphate, is an inhibitor of inosine monophosphate (IMP) dehydrogenase, but many other mechanisms of action are also supported with experimental evidence.

Antiviral agent. Its metabolite, ribavirin 5′-phosphate, is an inhibitor of inosine monophosphate (IMP) dehydrogenase. Used to inhibit purine (GTP pools) biosynthesis at the level of inosine monophosphate (IMP) dehydrogenase and as a precursor to the di- and tri-phosphates which inhibit viral RNA-dependent RNA polymerases.

UPC:
51131604
Condition:
New
HazmatClass:
No
MPN:
R9644-50MG
CAS:
36791-04-5

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