(Z)-RG-13022 is a tyrosine kinase ( TK ) inhibitor, which inhibits preferentially the TK activity of the EGF receptor and inhibits EGF-stimulated growth of cultured cells. (Z)-RG-13022 exerts an IC 50 of 11 μM for DNA synthesis in the HN5 cells, which is 3 times more potent than (E)-RG-13022 (IC 50 =38 μM). (Z)-RG-13022 can be used for research of breast cancer cells .
PubChem CID: 5468216
Isomeric SMILES: COC1=C(C=C(C=C1)/C=C(\C#N)/C2=CN=CC=C2)OC
- UPC:
- 41116105
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- R1357607-5mg
- Product Size:
- 5mg
- CAS:
- 149286-90-8
akash.verma@cenmed.com
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