FunctionGrowth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. May play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. Also binds the DEAR/FBXW7-AS1 receptor.
Specifictaions: ActiBioPure™, Recombinant, Animal Free, Carrier Free, High performance, ≥95%(SDS-PAGE)
Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/RP155249-SCI_44b4dbec0f9a12c0bb39dfea2e77793e.pdf
- UPC:
- 51152004
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- rp155249-10μg
- Product Size:
- 10μg
akash.verma@cenmed.com
(732) 447-1115





