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recombinant pim2 antibody (c09-1574-124)

Recombinant PIM2 Antibody (C007B-504988)

Catalog No.
C007B-504988
Manufacturer No.
Ab121878-1ml
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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Rabbit anti Human PIM2 Antibody, Recombinant, could be used for WB and so on.Application:WB: 1/500 - 1/1000Protein FunctionPromotes cell survival in response to a variety of proliferative signals via positive regulation of the I-kappaB

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Rabbit anti Human PIM2 Antibody, Recombinant, could be used for WB and so on.Application:WB: 1/500 - 1/1000Protein FunctionPromotes cell survival in response to a variety of proliferative signals via positive regulation of the I-kappaB kinase/NF-kappaB cascade; this process requires phosphorylation of MAP3K8/COT. Prevents apoptosis induced by growth factor withdrawal via inhibition of caspase-3 activation, and via phosphorylation of pro-apoptotic proteins. Inhibits BAD-induced cell death via phosphorylation of BAD. PIM2-mediated cell survival is glucose-dependent but independent of several AKT regulators such as PI3K, HSP-90 and TOR, indicating that PIM2 and PI3K/AKT/TOR function via distinct pathways. Involved in the positive regulation of chondrocyte survival and autophagy in the epiphyseal growth plate.Post-translationalAutophosphorylated.

Specifications and Purity: ExactAb™, Validated, Recombinant, 1.3 mg/mL

UPC:
41106618
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
Ab121878-1ml
Product Size:
1ml

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