Recombinant Mouse G-CSF Protein (C007B-319437)

Granulocyte colony stimulating factor (G-CSF) is a pleiotropic cytokine. It is mainly produced by monocytes and macrophages upon activation by endotoxin, TNF-α and IFN-γ. Besides, many other cell types can secret this protein after activation by LPS, IL-1 or TNF-α. Various carcinoma cell lines and myeloblastic leukemia cells can express G-CSF constitutively. G-CSF is cytokine that acts in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. In addition, it may function in some adhesion or recognition events at the cell surface. Human G-CSF is 73% identical at the amino acid level to murine G-CSF and the two proteins show species cross-reactivity. Recombinant murine G-CSF is an 18.9kDa polypeptide containing 178 amino acid residues.Purity>97% SDS-PAGEFunctionGranulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.

Specifications and Purity: ActiBioPure™, Bioactive, Carrier Free, Azide Free, High performance, ≥97%(SDS-PAGE&HPLC)