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Recombinant Human Sonic Hedgehog/Shh (C24II) Protein (C007B-543694)

Catalog No.
C007B-543694
Manufacturer No.
rp188214-1mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

Protein Function:Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also

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Protein Function:Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction.

Specifications and Purity: Carrier Free, ≥95%(SDS-PAGE)

UPC:
12161908
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
rp188214-1mg
Product Size:
1mg

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