Purity:>90%, by SDS-PAGE visualized with Coomassie® Blue Staining.Description: CFL1, also known as n-cofilin, is a member of the ADF/Cofilin family. This family comprises three genes: CFL1, CFL2 and DSTN (destrin). ADF/Cofilin family members bind G-actin monomers and depolymerize actin filaments through two mechanisms: severing and increasing the off-rate for actin monomers from the pointed end. Cofilin also binds with other proteins such as myosin, tropomyosin, α-actinin, gelsolin and scruin. These proteins compete with cofilin for actin binding. Сofilin also plays a role in innate immune response. CFL1 contains 1 ADF-H domain and is widely distributed in various tissues. It is important for normal progress through mitosis and normal cytokinesis.
Specifications and Purity: Carrier Free, Azide Free, ≥90%(SDS-PAGE)
- UPC:
- 41106510
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- rp169589-1mg
- Product Size:
- 1mg
akash.verma@cenmed.com
(732) 447-1115





