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rc-ome

RC-OME

Catalog No.
C005B-313642
Manufacturer No.
SML0228-25MG
Manufacturer Name
Sigma-Aldrich
Quantity
25
Unit of Measure
MG

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Application Rc-Ome may be used in GABA A -mediated cell signaling studies. Biochem/physiol Actions Rc-OMe is a GABA A PAM that distinguishes α: 1 β: 2γ:2s from α: 1 β: 2 receptors.

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Application

Rc-Ome may be used in GABAA-mediated cell signaling studies.

Biochem/physiol Actions

Rc-OMe is a GABAA PAM that distinguishes α1β2γ2s from α1β2 receptors. The compound has very weak potentiating effects on α1β2, but potentiates GABA-elicited currents of α(123)β2γ2s receptors, all with low μM EC50s. Rc-OMe acts at a binding site that is distinct from BDZ, pentobarbital and loreclezole modulatory sites.

Features and Benefits

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

UPC:
42202701
Condition:
New
HazmatClass:
No
MPN:
SML0228-25MG

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