RAS/RAS-RAF-IN-1 is a potent RAS and RAS-RAF inhibitor. RAS/RAS-RAF-IN-1 has a K D of 5.0 μΜ-15 μΜ for cyclophilin A (CYPA) binding affinity. RAS/RAS-RAF-IN-1 has antitumor activityIn VitroRAS/RAS-RAF-IN-1 (compound 89; for 4 hours) has an EC 50 of 0.5 μΜ-5.0 μΜ for BRAF-GTP-KRAS-G12C disruption and has an IC 50 of 1.0 μΜ-10 μΜ for pERK inhibition in H358 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:Ras RAF.
Molecular Formula: C45H57N7O7
Molecular Weight: 807.98
- UPC:
- 51131509
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- R646795-1mg
- CAS:
- 2447039-81-6
- Product Size:
- 1mg
akash.verma@cenmed.com
(732) 447-1115





