RAF265 (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM. Phase 2.An orally-bioavailable, selective, potent inhibitor of B-Raf and VEGFR-2.
Specifications and Purity: ≥98%
Molecular Formula: C24H16F6N6O
Molecular Weight: 518.43
PubChem CID: 11656518
Isomeric SMILES: CN1C2=C(C=C(C=C2)OC3=CC(=NC=C3)C4=NC=C(N4)C(F)(F)F)N=C1NC5=CC=C(C=C5)C(F)(F)F
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/R127906-SCI_28c39278b431079fd3fd66665248b246.pdf
- UPC:
- 41106403
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- R127906-50mg
- CAS:
- 927880-90-8
- Product Size:
- 50mg
akash.verma@cenmed.com
(732) 447-1115





