RAD51-IN-1, a derivative of B02, is a potent inhibitor of RAD51. RAD51-IN-1 can be used for cancer research.In VitroRAD51 is a vital component of the homologous recombination DNA repair pathway and is overexpressed in drug-resistant cancers, including aggressive triple-negative breast cancer (TNBC). RAD51-IN-1 (10 μM) decreases the ratio of RAD51 positive cells/cH2AX positive cells in MDA-MB-231 cell exposure to 6 Gy irradiation. RAD51-IN-1 (10 μM) significantly inhibits DNA damage induced RAD51 foci formation with 6 Gy irradiation. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Specifications and Purity: 10mM in DMSO
Molecular Formula: C22H16ClN3O
Molecular Weight: 373.8
- UPC:
- 41106006
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- R656046-1ml
- CAS:
- 2101739-18-6
- Product Size:
- 1ml
akash.verma@cenmed.com
(732) 447-1115





