Application
R-(−)-Fluoxetine hydrochloride has been used as a serotonin reuptake inhibitor:
- to study its effects on the embryoid body (EB) morphogenesis
- in combination with muscimol hydrobromide (MUS) as well as individually to study its neurotoxic effects on neuronal cells grown on multielectrode array (MEA) chips
- to study its effects as an endocrine disruption inducer in Pimephales promelas
Biochem/physiol Actions
Fluoxetine exhibits anti-depressant activity by increasing the serotonin levels in the neuron synaptic space. It also exhibits therapeutic effects against depression and other mood disorders.
Selective serotonin reuptake inhibitor.
Features and Benefits
This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Molecular Weight: 345.79. Empirical Formula: C17H18NOF3 · HCl. Quality Level: 100. Assay: >. 98% (HPLC). form: solid. storage condition: desiccated. color: white. solubility: H2O: soluble >. 10 . mg/mL. originator: Eli Lilly. SMILES string: Cl[H].CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c2ccccc2. InChI: 1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20. /h2-10,16,21H,11-12H2,1H3. 1H/t16-. /m1./s1. InChI key: GIYXAJPCNFJEHY-PKLMIRHRSA-N. Gene Information: human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363). Pictograms: GHS05,GHS07. Signal Word: Danger. Hazard Statements: H302 - H315 - H318. Precautionary Statements: P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310. Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves.- UPC:
- 51101510
- Condition:
- New
- HazmatClass:
- No
- MPN:
- F1678-5MG
- CAS:
- 114247-09-5
akash.verma@cenmed.com
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