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R-(-)-FLUOXETINE HYDROCHLORIDE (C005B-009663)

Catalog No.
C005B-009663
Manufacturer No.
F1678-5MG
Manufacturer Name
Sigma-Aldrich
Quantity
5
Unit of Measure
MG

Application R -(−)-Fluoxetine hydrochloride has been used as a serotonin reuptake inhibitor: to study its effects on the embryoid body (EB) morphogenesis in combination with muscimol hydrobromide (MUS) as well as individually to study its

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Application

R-(−)-Fluoxetine hydrochloride has been used as a serotonin reuptake inhibitor:

  • to study its effects on the embryoid body (EB) morphogenesis
  • in combination with muscimol hydrobromide (MUS) as well as individually to study its neurotoxic effects on neuronal cells grown on multielectrode array (MEA) chips
  • to study its effects as an endocrine disruption inducer in Pimephales promelas

Biochem/physiol Actions

Fluoxetine exhibits anti-depressant activity by increasing the serotonin levels in the neuron synaptic space. It also exhibits therapeutic effects against depression and other mood disorders.

Selective serotonin reuptake inhibitor.

Features and Benefits

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Molecular Weight: 345.79. Empirical Formula: C17H18NOF3 · HCl. Quality Level: 100. Assay: >. 98% (HPLC). form: solid. storage condition: desiccated. color: white. solubility: H2O: soluble >. 10 . mg/mL. originator: Eli Lilly. SMILES string: Cl[H].CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c2ccccc2. InChI: 1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20. /h2-10,16,21H,11-12H2,1H3. 1H/t16-. /m1./s1. InChI key: GIYXAJPCNFJEHY-PKLMIRHRSA-N. Gene Information: human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363). Pictograms: GHS05,GHS07. Signal Word: Danger. Hazard Statements: H302 - H315 - H318. Precautionary Statements: P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310. Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves.
UPC:
51101510
Condition:
New
HazmatClass:
No
MPN:
F1678-5MG
CAS:
114247-09-5

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