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QCA570 (C007B-414602)

Catalog No.
C007B-414602
Manufacturer No.
Q650136-10mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

QCA570 is a PROTAC connected by ligands for Cereblon and BET , with an IC 50 of 10 nM for BRD4 BD1 Protein.In VitroQCA570 is an extremely potent and highly efficacious BET degrader, capable of degrading BET proteins at low picomolar (pM)

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QCA570 is a PROTAC connected by ligands for Cereblon and BET , with an IC 50 of 10 nM for BRD4 BD1 Protein.In VitroQCA570 is an extremely potent and highly efficacious BET degrader, capable of degrading BET proteins at low picomolar (pM) concentrations in leukemia cells. QCA570 inhibits cell growth in MV4;11, MOLM-13, and RS4;11 cell lines with IC 50 values of 8.3, 62, and 32 pM, respectively. QCA570 is the most potent and efficacious BET degrader reported to date. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:BRD4 BD1 10 nM (IC 50 ).

Specifications and Purity: ≥99%

Molecular Formula: C39H33N7O4S

Molecular Weight: 695.79

PubChem CID: 134348221

UPC:
41113405
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
Q650136-10mg
CAS:
2207569-08-0
Product Size:
10mg

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