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PYRILAMINE MALEATE CRYSTALLINE (C005B-438978)

Catalog No.
C005B-438978
Manufacturer No.
P5514-100G
Manufacturer Name
Sigma-Aldrich
Quantity
100
Unit of Measure
GM

Application Pyrilamine maleate salt has been used: to treat Cassiopea sp. as H 1 receptor antagonist to intraperitoneally inject mice to prevent the release of endogenous histamine in membrane binding assay to determine the K i values

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Application

Pyrilamine maleate salt has been used:

  • to treat Cassiopea sp. as H1 receptor antagonist
  • to intraperitoneally inject mice to prevent the release of endogenous histamine
  • in membrane binding assay to determine the Ki values and in the comparative inhibitory concentration (IC50) studies by whole-cell patch clamp technique

Biochem/physiol Actions

Pyrilamine maleate is a H1 histamine receptor antagonist. Pyrilamine maleate induces sleep in vertebrates. In Cassiopea, it induces concentration dependent dormancy.

Features and Benefits

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Watson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

UPC:
12131600
Condition:
New
HazmatClass:
No
MPN:
P5514-100G
CAS:
59-33-6

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