Mepyramine maleate, a first generation antihistamine, is an antagonist of histamine H1 receptor, with Kds of 0.8 nM, 5200 nM and >3000 nM for H1, H2, and H3 receptor, respectively, and a pKd of 9.4 for H1 receptor.application:Pyrilamine maleate salt has been used:to treat Cassiopea sp. as H1 receptor antagonistto intraperitoneally inject mice to prevent the release of endogenous histaminein membrane binding assay to determine the Ki values and in the comparative inhibitory concentration (IC50) studies by whole-cell patch clamp technique.
Specifications and Purity: 10mM in DMSO
Molecular Formula: C17H23N3O · C4H4O4
Molecular Weight: 401.46
PubChem CID: 5284451
Isomeric SMILES: CN(C)CCN(CC1=CC=C(C=C1)OC)C2=CC=CC=N2.C(=C/C(=O)O)/C(=O)O
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/P424946-SCI_e498151c5c4259a2b5cc1d7b04767e2a.pdf
- UPC:
- 12131600
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- P424946-1ml
- CAS:
- 59-33-6
- Product Size:
- 1ml
- Hazard Statement Codes:
- H302
- Precautionary Statement Codes:
- P301+P312:P264
akash.verma@cenmed.com
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