Puromycin aminonucleoside (C007B-249067)

Puromycin Aminonucleoside (3'-Amino-3'-deoxy-N6,N6-dimethyladenosine) is the aminonucleoside portion of the antibiotic puromycin. It is a puromycin analog which does not inhibit protein synthesis or induce apoptosis. Used in the study of focal and segmental glomerulosclerosis and in the induction of nephrosis in rats. The excretion of sodium and NOx metabolites in rats with puromycin aminonucleoside-induced nephrotic syndrome has been studied. Used to probe endothelial glycosaminoglycan synthesis in cultured glomerular endothelial cells and their relation to cell permeabilityThe aminonucleoside portion of the antibiotic puromycin.

Specifications and Purity: 10mM in DMSO

Molecular Formula: C12H18N6O3

Molecular Weight: 294.31

EC Number: 200-388-3

PubChem CID: 6020

Isomeric SMILES: CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)N)O

Beilstein Registry Number: 93902