PSB-12379 (C007B-386801)

Catalog No.: C007B-386801
Manufacturer No.: P655974-1ml
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

PSB-12379, a nucleotide analogue, is a potent Ecto-5'-Nucleotidase ( CD73 ) inhibitor with K i s of 9.03 nM (rat) and 2.21 nM (human)In VitroMetabolism : Only a small percentage (<23%) of PSB-12379 (10g) is metabolized under the applied conditions, while >77% of the compounds are recovered unchanged after a long incubation for 8 h. PSB-12379 (10g) is somewhat less stable, and 56% are metabolized within 8 h. Hydrolytic cleavage of the glycosidic bond, which is a typical phase I reaction of nucleosides and nucleotides, was observed as the main reaction. MCE has not independently confirmed the accuracy of these methods. They are for reference only.IC50& Target:Ki: 9.03 nM (rat), 2.21 nM (human) (Ecto-5’-Nucleotidase).

Specifications and Purity: 10mM in Water

Molecular Formula: C18H23N5O9P2

Molecular Weight: 515.35

UPC:: 51171607
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: P655974-1ml
CAS:: 1802226-78-3
Product Size:: 1ml

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