PSB-12062 (C007B-385374)

Catalog No.: C007B-385374
Manufacturer No.: P646739-5mg
Manufacturer Name: Aladdin Scientific
Quantity: 1
Unit of Measure: EA

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Description
Specifications

PSB-12062 is a potent and selective P2X4 antagonist with an IC 50 of 1.38 μM for human P2X4.In VitroPSB-12062 shows similar potency in human, rat, and mouse species. PSB-12062 shows to be allosteric in nature with a 35-fold selectivity toward P2X4 versus P2X1, P2X2, P2X3, and P2X7. However, PSB-12062 is unable to completely block ATP-induced P2X4-mediated calcium influx even when used at high concentrations (>30 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:IC50: 1.38 μM (human P2X4), 92.8 nM (rat P2X4), 1.76 μM (mouse P2X4).

Specifications and Purity: ≥99%

Molecular Formula: C19H15NO3S

Molecular Weight: 337.39

PubChem CID: 2320735

Isomeric SMILES: CC1=CC=C(C=C1)S(=O)(=O)N2C3=CC=CC=C3OC4=CC=CC=C42

UPC:: 41103025
Condition:: New
HazmatClass:: No
WeightUOM:: LB
MPN:: P646739-5mg
CAS:: 55476-47-6
Product Size:: 5mg

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