Prostaglandin E2 Ethanolamide (C007B-412894)

Prostaglandin E2 Ethanolamide is an analog of PGE2 with improved water solubility and stability that has demonstrated the ability to induce apoptosis in HT29 and HCA7/C29 human colorectal carcinoma (CRC) cell lines. Shown to act as an agonist with all four known EP receptor subtypes (EP1 - EP4), but with an affinity that is significantly less than PGE2. This compound is thought to be biosyntesized via COX-2 from the precursor anandamide , the endogenous cannabinoid neurotransmitter. These prostaglandin analogues are integral for structure-activity studies used in the deconvolution of these complex biochemical pathways, and in this case demonstrates unique and applicable biochemical activity.

Specifications and Purity: ≥98%

Molecular Formula: C22H37NO5

Molecular Weight: 395.5

PubChem CID: 5283119

Isomeric SMILES: CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1C/C=C/CCCC(=O)NCCO)O)O

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