2-Arachidonyl glycerol (2-AG) exhibits CB agonist activity at the CB1 receptor, is an important endogenous monoglyceride species,{6819} and is thus considered to be the natural ligand for the CB1 receptor. 2-AG can also be metabolized by COX-2 to form PG 2-glyceryl esters. In activated RAW 264.7 cells, PGD2 2-glyceryl ester is the primary product of 2-AG metabolism in the COX pathway. PGD2-SA is a stable analog of PGD2 2-glyceryl ester. Unlike PGD2 2-glyceryl ester and other fatty acyl 2-glyceryl esters, PGD2-SA will not isomerize to the less active primary (1-glyceryl) ester. The biological activity of PGD2-SA has not yet been determined.
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- UPC:
- 51182007
- HazmatClass:
- Yes
- WeightUOM:
- LB
- MPN:
- 10192-1
- CAS:
- 851761-42-7
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