Application
Prostaglandin B2 has been used as an internal standard in high-performance liquid chromatography (HPLC).
Biochem/physiol Actions
Prostaglandin B2 (PGB2) is an eicosanoid and a lipid mediator. It is synthesized by the dehydration of PGE2. It is a primary prostaglandin associated with the osteoblasts and may induce pulmonary hypertension. PGB2 is also reported to inhibit glucagon stimulated glycogenolysis and forskolin-stimulated adenylate cyclase activity in plasma membranes.
Physical form
Prostaglandin B2 is supplied as a solution in methyl acetate
Preparation Note
PGB2 is provided as a solution in methyl acetate. To change the solvent, evaporate the methyl acetate under a gentle stream of nitrogen and immediately add the solvent of choice. PGB2, purged with an inert gas, is soluble in ethanol at ~100 mg/mL, DMSO at ~50 mg/mL and in dimethyl formamide at ~ 75 mg/mL.
- UPC:
- 51142507
- Condition:
- New
- HazmatClass:
- Yes
- MPN:
- P5390-1MG
- CAS:
- 13367-85-6
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