Polymyxin B nonapeptide TFA (C007B-386864)

Polymyxin B nonapeptide TFA is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide TFA is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes .In VitroPolymyxin B nonapeptide, a cationic cyclic peptide derived by enzymatic processing from the naturally occurring peptide polymyxin B, is able to increase the permeability of the outer membrane of Gram-negative bacteria toward hydrophobic antibiotics probably by binding to the bacterial lipopolysaccharide (LPS). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Specifications and Purity: 10mM in Water

Molecular Formula: C53H79F15N14O21

Molecular Weight: 1533.3