POLY-L-ARGININE HCL MOL WT 15000-70000 (C005B-438336)

Catalog No.: C005B-438336
Manufacturer No.: P7762-100MG
Manufacturer Name: Sigma-Aldrich
Quantity: 100
Unit of Measure: MG

General description Poly- L -arginine hydrochloride (PLA) is a homopolyamino acid. PLA enhances membrane permeability compared to poly- L -lysine.

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Description
Specifications

General description

Poly-L-arginine hydrochloride (PLA) is a homopolyamino acid. PLA enhances membrane permeability compared to poly-L-lysine. It has applications as drug carrier, neuroprotective agent and in anticancer vaccines preparations. Peptide vaccines in conjugation with PLA promotes antigen-presenting cells (APCs) to generate T cell and elicit immunostimulant functionality.

Application

Poly-L-arginine hydrochloride has been used:

to generate complex with stimulatory RNA isRNA9.2 as in neutrophils
used in ribosomal RNA transfection into human monocytic THP-1 cells
for coating alginate capsule beads

Quality

Contains 3% or less ornithine residue.

Analysis Note

Molecular weight based on viscosity of precursor poly-L-ornithine. Also assayed by MALLS.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

UPC:: 51191520
Condition:: New
HazmatClass:: No
MPN:: P7762-100MG
CAS:: 26982-20-7

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