PIMECROLIMUS (C005B-312110)

Catalog No.: C005B-312110
Manufacturer No.: SML1437-10MG
Manufacturer Name: Sigma-Aldrich
Quantity: 10
Unit of Measure: MG

Biochem/physiol Actions Pimecrolimus is known for its anti-inflammatory and immunomodulatory properties and its low systemic immunosuppressive potential. Pimecrolimus, also known as Picrolimus, is a macrolactam ascomycin derivative that acts as

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Description
Specifications

Biochem/physiol Actions

Pimecrolimus is known for its anti-inflammatory and immunomodulatory properties and its low systemic immunosuppressive potential.

Pimecrolimus, also known as Picrolimus, is a macrolactam ascomycin derivative that acts as an immune suppressant. It binds with high affinity to macrophilin-12 (FKBP-12) and inhibits calcineurin, a calcium-dependent phosphatase. Pimecrolimus inhibits production of pro-inflammatory cytokines by T cells and mast cells and prevents the release of inflammatory cytokines and mediators from mast cells. It has been used clinically as a treatment for eczema.

UPC:: 51152006
Condition:: New
HazmatClass:: No
MPN:: SML1437-10MG
CAS:: 137071-32-0

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