Pibrentasvir (ABT-530) (C007B-248639)

InformationPibrentasvir (ABT-530) Pibrentasvir (ABT-530) is a novel and pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with EC50 ranging from 1.4 pM to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6.TargetsGT5a (Cell-free assay); GT1a H77 (Cell-free assay); GT2b (Cell-free assay); GT4a (Cell-free assay); GT3a (Cell-free assay) 33615,1.4 pM(EC50); 1.8 pM(EC50); 1.9 pM(EC50); 1.9 pM(EC50); 2.1 pM(EC50)In vitroPibrentasvir is a next-generation HCV NS5A inhibitor with potent and pan-genotypic activity, and it maintains activity against common amino acid substitutions of HCV genotypes 1 to 6 that are known to confer resistance to currently approved NS5A inhibitors.Cell Research(from reference)Cell lines：Huh-7 human hepatoma cell line, CEM-SS cells Incubation Time：6 days.

Specifications and Purity: ≥98%

Molecular Formula: C57H65F5N10O8

Molecular Weight: 1113.18

PubChem CID: 58031952

Isomeric SMILES: C[C@H]([C@@H](C(=O)N1CCC[C@H]1C2=NC3=C(N2)C=C(C(=C3)F)[C@H]4CC[C@@H](N4C5=CC(=C(C(=C5)F)N6CCC(CC6)C7=CC=C(C=C7)F)F)C8=CC9=C(C=C8F)N=C(N9)[C@@H]1CCCN1C(=O)[C@H]([C@@H](C)OC)NC(=O)OC)NC(=O)OC)OC

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