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phosphonoacetic acid (c15-1239-338)

PHOSPHONOACETIC ACID 98% (C005B-040153)

Catalog No.
C005B-040153
Manufacturer No.
284270-50G
Manufacturer Name
Sigma-Aldrich
Quantity
50
Unit of Measure
GR

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Phosphonoacetic acid inhibits specifically human cytomegalovirus DNA synthesis in virus-infected human fibroblasts . It also inhibits the synthesis of herpes simplex virus DNA in infected cells and the activity of the virus-specific DNA polymerase

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General description

Phosphonoacetic acid inhibits specifically human cytomegalovirus DNA synthesis in virus-infected human fibroblasts. It also inhibits the synthesis of herpes simplex virus DNA in infected cells and the activity of the virus-specific DNA polymerase in vitro.

Application

Phosphonoacetic acid was used as an inhibitor of viral DNA replication, to investigate the infected cell protein 0 (bICP0) localization in infected low passage bovine cells. It was also used as a phosphorus source for microbial growth in phosphate-independent manner.

Molecular Weight: 140.03. Empirical Formula: C2H5O5P. linearFormula: (HO)2P(O)CH2CO2H. Quality Level: 100. Assay: 98%. form: powder or crystals. mp: 143-146 . °C (lit.). solubility: water: soluble 100 . mg/mL, clear to very slightly hazy, colorless. SMILES string: OC(: O)CP(O)(O): O. InChI: 1S/C2H5O5P/c3-2(4)1-8(5,6)7/h1H2,(H,3,4)(H2,5,6,7). InChI key: XUYJLQHKOGNDPB-UHFFFAOYSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves.
UPC:
51182416
Condition:
New
HazmatClass:
No
MPN:
284270-50G
CAS:
4408-78-0

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